Association between osteocalcin, a pivotal marker of bone metabolism, and secretory function of islet beta cells and alpha cells in Chinese patients with type 2 diabetes mellitus: an observational study

Association between osteocalcin, a pivotal marker of bone metabolism, and secretory function of islet beta cells and alpha cells in Chinese patients with type 2 diabetes mellitus: an observational study

Abstract Background Several recent studies have found that Osteocalcin (OCN), a multifunctional protein secreted exclusively by osteoblasts, is beneficial to glucose metabolism and type 2 diabetes mellitus (T2DM). However, the effects of OCN on islets function especially islet ɑ cells function in pa...

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Bibliographic Details
Main Authors: Haiyan Lei, Jun Liu, Wei Wang, Xinyi Yang, Zhouqin Feng, Pu Zang, Bin Lu, Jiaqing Shao
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Serum osteocalcin
Blood glucose
Pancreatic secretion
Glucagon secretion
Type 2 diabetes mellitus
Online Access:https://doi.org/10.1186/s13098-022-00932-8

Internet

https://doi.org/10.1186/s13098-022-00932-8

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