Association between osteocalcin, a pivotal marker of bone metabolism, and secretory function of islet beta cells and alpha cells in Chinese patients with type 2 diabetes mellitus: an observational study

Abstract Background Several recent studies have found that Osteocalcin (OCN), a multifunctional protein secreted exclusively by osteoblasts, is beneficial to glucose metabolism and type 2 diabetes mellitus (T2DM). However, the effects of OCN on islets function especially islet ɑ cells function in pa...

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Detalhes bibliográficos
Principais autores: Haiyan Lei, Jun Liu, Wei Wang, Xinyi Yang, Zhouqin Feng, Pu Zang, Bin Lu, Jiaqing Shao
Formato: Artigo
Idioma:English
Publicado em: BMC 2022-10-01
coleção:Diabetology & Metabolic Syndrome
Assuntos:
Acesso em linha:https://doi.org/10.1186/s13098-022-00932-8