CCK1-Receptor Stimulation Protects Against Gut Mediator-Induced Lung Damage During Endotoxemia

CCK1-Receptor Stimulation Protects Against Gut Mediator-Induced Lung Damage During Endotoxemia

Background/Aims: Cholecystokinin 1-receptor (CCK1-R) activation by long chain fatty acid (LCFA) absorption stimulates vago-vagal reflex pathways in the brain stem. The present study determines whether this reflex also activates the cholinergic anti-inflammatory pathway, a pathway known to modulate c...

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Bibliographic Details
Main Authors: Friederike Eisner, Elizabeth M. Martin, Markus A. Küper, Helen E. Raybould, Jörg Glatzle
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Sepsis
Endotoxemia
Innate immunity
Mucosal immunity
Cholinergic anti-inflammatory pathway
Cholecystokinin
Online Access:http://www.karger.com/Article/FullText/356644

Internet

http://www.karger.com/Article/FullText/356644

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