Natural reward experience alters AMPA and NMDA receptor distribution and function in the nucleus accumbens.

Natural reward and drugs of abuse converge upon the mesolimbic system which mediates motivation and reward behaviors. Drugs induce neural adaptations in this system, including transcriptional, morphological, and synaptic changes, which contribute to the development and expression of drug-related mem...

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Bibliographic Details
Main Authors: Kyle K Pitchers, Susanne Schmid, Andrea R Di Sebastiano, Xu Wang, Steven R Laviolette, Michael N Lehman, Lique M Coolen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3329487?pdf=render