The Humanised NPY-mRFP RBL Reporter Cell Line Is a Fast and Inexpensive Tool for Detection of Allergen-Specific IgE in Human Sera

Rat basophilic leukaemia (RBL) cells have been used for decades as a model of high-affinity Immunoglobulin E (IgE) receptor (FcεRI) signalling. Here, we describe the generation and use of huNPY-mRFP, a new humanised fluorescent IgE reporter cell line. Fusion of Neuropeptide Y (NPY) with monomeric re...

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Detaylı Bibliyografya
Asıl Yazarlar: Prema S. Prakash, Nafal J. S. Barwary, Michael H. W. Weber, Daniel Wan, Iván Conejeros, Bernardo Pereira Moreira, Waleed S. Alharbi, Jaap J. van Hellemond, Jude Akinwale, Franco H. Falcone
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: MDPI AG 2022-08-01
Seri Bilgileri:Diagnostics
Konular:
Online Erişim:https://www.mdpi.com/2075-4418/12/9/2063