BRAF V600E-Mutant Glioblastoma with Extracranial Metastases Responsive to Combined BRAF and MEK Targeted Inhibition: A Case Report

Recent advancements in understanding the biology of glioblastomas (GBM) and increasing adoption of genomic sequencing in oncology practice have led to the discovery of several targetable mutations in these cancers. Among them, the BRAF V600E mutation can be found in approximately 3% of GBM. Despite...

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Bibliographic Details
Main Authors: Vasu Munjapara, Thatcher Heumann, Karisa C. Schreck, John M. Gross, Carlos Perez-Heydrich, Sachin K. Gujar, Charles G. Eberhart, Matthias Holdhoff
Format: Article
Language:English
Published: Karger Publishers 2022-10-01
Series:Case Reports in Oncology
Subjects:
Online Access:https://www.karger.com/Article/FullText/525660