Underlying beneficial effects of Rhubarb on constipation-induced inflammation, disorder of gut microbiome and metabolism

Background: Constipation is a common syndrome and a worldwide healthy problem. Constipation patients are becoming younger, with a 29.6% overall prevalence in children, which has captured significant attention because of its epigenetic rejuvenation and recurrent episodes. Despite the usage of rhubarb...

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Bibliographic Details
Main Authors: Han Gao, Chengwei He, Rongxuan Hua, Chen Liang, Boya Wang, Yixuan Du, Shuzi Xin, Yuexin Guo, Lei Gao, Lucia Zhang, Hongwei Shang, Jingdong Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1048134/full