Heterozygous variants of NOD2, IL10RA, PLA2G6 and COL7A1 correlate with Crohn's disease

Heterozygous variants of NOD2, IL10RA, PLA2G6 and COL7A1 correlate with Crohn's disease

To identify candidate pathogenic genes of early-stage Crohn's disease (CD) and predict potential roles of genetic factors in CD, we performed whole exome sequencing on a child with early-stage Crohn's disease (CD) and her parents (core family), found that the patient carried heterozygous v...

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Bibliographic Details
Main Authors: Qiang Zhang, Xizi Wang, Juan Zheng, Qiang Lü, Rongrong Li, Xiaodong Jia, Mingliang Gu
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
Crohn's disease
Whole exome sequencing
NOD2
IL10RA
PLA2G6
COL7A1
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023101769

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http://www.sciencedirect.com/science/article/pii/S2405844023101769

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