Atypical PKC and Notch Inhibition Differentially Modulate Cortical Interneuron Subclass Fate from Embryonic Stem Cells

Atypical PKC and Notch Inhibition Differentially Modulate Cortical Interneuron Subclass Fate from Embryonic Stem Cells

Recent studies indicate that the location of neurogenesis within the medial ganglionic eminence (MGE) critically influences the fate determination of cortical interneuron subgroups, with parvalbumin (Pv) interneurons originating from subventricular zone divisions and somatostatin (Sst) interneurons...

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Bibliographic Details
Main Authors: David J. Tischfield, Junho Kim, Stewart A. Anderson
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Stem Cell Reports
Subjects:
cortical interneurons
embryonic stem cells
fate specification
parvalbumin
somatostatin
mouse
atypical PKC
intermediate neurogenesis
cyclin D2
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117301212

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http://www.sciencedirect.com/science/article/pii/S2213671117301212

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