Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age

Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age

Lipids are closely associated with brain structure and function. However, the potential changes in the lipidome induced by aging remain to be elucidated. In this study, we used chromatographic techniques and a mass spectrometry-based approach to evaluate age-associated changes in the lipidome of the...

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Bibliographic Details
Main Authors: Mariona Jové, Rosanna Cabré, Natàlia Mota-Martorell, Meritxell Martin-Garí, Èlia Obis, Paula Ramos, Iván Canales, José Daniel Galo-Licona, Joaquim Sol, Lara Nogueras, Pascual Torres, Manuel Portero-Otín, Victòria Ayala, Isidro Ferrer, Reinald Pamplona
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
aging
glycerolipids
glycerophospholipids
(lip)oxidation-derived protein damage markers
mass spectrometry
methionine restriction
Online Access:https://www.mdpi.com/1422-0067/22/22/12517

Internet

https://www.mdpi.com/1422-0067/22/22/12517

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