Estradiol-independent restoration of T-cell function in post-reproductive females

Aging leads to a general decline in protective immunity. The most common age-associated effects are in seen T-cell mediated immune function. Adult mice whose immune systems show only moderate changes in T-cell subsets tend to live longer than age-matched siblings that display extensive T-cell subset...

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Bibliographic Details
Main Authors: Tristin L. King, B. Shaun Bryner, Kaden B. Underwood, McKenna R. Walters, Shawn M. Zimmerman, Nathan K. Johnson, Jeffrey B. Mason
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1066356/full