The effect of food intake on the pk of rhein released from diacerein

Diacerein is a symptomatic slow-acting drug used for treating osteoarthritis. This drug is completely metabolized into the active metabolite rhein before reaching the systemic circulation. This study evaluated the effects of food on the pharmacokinetics of rhein released from diacerein in healthy Ch...

Full description

Bibliographic Details
Main Authors: Ming Huang, Shun-lin Zong, Quan-ying Zhang
Format: Article
Language:English
Published: Universidade de São Paulo 2020-04-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100544&tlng=en