Olmesartan Attenuates Single-Lung Ventilation Induced Lung Injury via Regulating Pulmonary Microbiota

Olmesartan Attenuates Single-Lung Ventilation Induced Lung Injury via Regulating Pulmonary Microbiota

Single-lung ventilation (SLV) associated acute lung injury is similar to ischemia reperfusion (IR) injury which is usually occurred during lung surgery. Olmesartan (Olm), a novel angiotensin receptor blocker (ARB), has been reported to ameliorate organ IR injury. Several recent studies have shown th...

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Bibliographic Details
Main Authors: Di Lu, Zhizhi Wang, Zhiming Chen, Jiayang Fan, Jianxue Zhai, Duopei Fang, He Cai, Xiguang Liu, Hua Wu, Kaican Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Pharmacology
Subjects:
pulmonary microbiota
metabolite
single-lung ventilation
lung injury
angiotensin receptor blocker
olmesartan
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.822615/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.822615/full

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