Reparative properties of human glioblastoma cells after single exposure to a wide range of X-ray doses

Reparative properties of human glioblastoma cells after single exposure to a wide range of X-ray doses

Radiation therapy induces double-stranded DNA breaks in tumor cells, which leads to their death. A fraction of glioblastoma cells repair such breaks and reinitiate tumor growth. It was necessary to identify the relationship between high radiation doses and the proliferative activity of glioblastoma...

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Bibliographic Details
Main Authors: Galina Pavlova, Alexandra Belyashova, Ekaterina Savchenko, Dmitri Panteleev, Dzhirgala Shamadykova, Anna Nikolaeva, Svetlana Pavlova, Alexander Revishchin, Denis Golbin, Alexander Potapov, Natalia Antipina, Andrey Golanov
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
human glioblastoma cell cultures
radiation therapy
Rad51
Ku70
Ku80
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.912741/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.912741/full

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