Efficient generation of functional pancreatic β cells from dental-derived stem cells via laminin-induced differentiation

Efficient generation of functional pancreatic β cells from dental-derived stem cells via laminin-induced differentiation

Abstract Background This study was designed to generate functional insulin-producing cells (IPCs) from dental-derived mesenchymal stem cells (MSCs) and further explore their therapeutic potential against diabetes mellitus in vivo. MSCs were isolated from human dental pulp and periodontal ligament an...

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Bibliographic Details
Main Authors: Riham M. Aly, Hadeer A. Aglan, Ghada Nour Eldeen, Nadia S. Mahmoud, Eman H. Aboul-Ezz, Hanaa H. Ahmed
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Dental stem cells
Insulin-producing cells
Diabetes mellitus
Laminin
Differentiation
Online Access:https://doi.org/10.1186/s43141-022-00369-6

Internet

https://doi.org/10.1186/s43141-022-00369-6

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