Guanabenz Acetate Induces Endoplasmic Reticulum Stress–Related Cell Death in Hepatocellular Carcinoma Cells

Guanabenz Acetate Induces Endoplasmic Reticulum Stress–Related Cell Death in Hepatocellular Carcinoma Cells

Background Development of chemotherapeutics for the treatment of advanced hepatocellular carcinoma (HCC) has been lagging. Screening of candidate therapeutic agents by using patient-derived preclinical models may facilitate drug discovery for HCC patients. Methods Four primary cultured HCC cells fro...

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Bibliographic Details
Main Authors: Hyo Jeong Kang, Hyang Sook Seol, Sang Eun Lee, Young-Ah Suh, Jihun Kim, Se Jin Jang, Eunsil Yu
Format: Article
Language:English
Published: Korean Society of Pathologists & the Korean Society for Cytopathology 2019-03-01
Series:Journal of Pathology and Translational Medicine
Subjects:
Hepatocellular carcinoma
Primary cell culture
Drug sensitivity
Drug repositioning
Guanabenz acetate
Online Access:http://www.jpatholtm.org/upload/pdf/jptm-2019-01-14.pdf

Internet

http://www.jpatholtm.org/upload/pdf/jptm-2019-01-14.pdf

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