Current status of intensified neo-adjuvant systemic therapy in locally advanced rectal cancer

The addition of 5-fluorouracil (5-FU) or its prodrug capecitabine to radiotherapy (RT) is a standard approach in the neo-adjuvant treatment of patients with rectal tumors extending beyond the muscularis propria (stage II) and/or with clinical evidence of regional lymph node metastases (stage III). A...

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Bibliographic Details
Main Authors: Benedikt eEngels, Thierry eGevaert, Alexandra eSermeus, Mark eDe Ridder
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00047/full