Analysis of 24-h Rhythm in Ventricular Repolarization Identifies QT Diurnality As a Novel Clinical Parameter Associated with Previous Ventricular Arrhythmias in Heart Failure Patients

Analysis of 24-h Rhythm in Ventricular Repolarization Identifies QT Diurnality As a Novel Clinical Parameter Associated with Previous Ventricular Arrhythmias in Heart Failure Patients

Introduction: Cardiac repolarization abnormalities are among the major causes of ventricular arrhythmias and sudden cardiac death. In humans, cardiac repolarization duration has a 24-h rhythm. Animal studies show that this rhythm is regulated by 24-h rhythms in ion channel function and that disrupti...

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Bibliographic Details
Main Authors: Bastiaan C. Du Pre, Linda W. Van Laake, Matthias Meine, Jeroen F. Van der Heijden, Pieter A. Doevendans, Marc A. Vos, Toon A. B. Van Veen
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Physiology
Subjects:
circadian
repolarization
QT
ventricular arrhythmia
sudden cardiac death
rhythm
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00590/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2017.00590/full

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