Simvastatin ameliorates established pulmonary hypertension through a heme oxygenase-1 dependent pathway in rats

<p>Abstract</p> <p>Background</p> <p>Simvastatin has been shown to ameliorate pulmonary hypertension by several mechanisms in experimental animal models. In this study, we hypothesized that the major benefits of simvastatin in pulmonary hypertension occur via the heme o...

Full description

Bibliographic Details
Main Authors: Lee Yung-Chie, Chen Jin-Shing, Hsu Jo-Yu, Ko Wen-Je, Hsu Hsao-Hsun, Lai I-Rue, Chen Chau-Fong
Format: Article
Language:English
Published: BMC 2009-05-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/10/1/32