A Triple Gene-Deleted Pseudorabies Virus-Vectored Subunit PCV2b and CSFV Vaccine Protects Pigs against PCV2b Challenge and Induces Serum Neutralizing Antibody Response against CSFV

A Triple Gene-Deleted Pseudorabies Virus-Vectored Subunit PCV2b and CSFV Vaccine Protects Pigs against PCV2b Challenge and Induces Serum Neutralizing Antibody Response against CSFV

Porcine circovirus type 2 (PCV2) is endemic worldwide. PCV2 causes immunosuppressive infection. Co-infection of pigs with other swine viruses, such as pseudorabies virus (PRV) and classical swine fever virus (CSFV), have fatal outcomes, causing the swine industry significant economic losses in many...

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Bibliographic Details
Main Authors: Selvaraj Pavulraj, Katrin Pannhorst, Rhett W. Stout, Daniel B. Paulsen, Mariano Carossino, Denise Meyer, Paul Becher, Shafiqul I. Chowdhury
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Vaccines
Subjects:
pseudorabies virus
triple mutant
vectored vaccine
PCV2 capsid
CSFV
glycoproteins E2 and Erns
Online Access:https://www.mdpi.com/2076-393X/10/2/305

Internet

https://www.mdpi.com/2076-393X/10/2/305

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