Altered phospholipid-apoB-100 interactions and generation of extra membrane material in proteolysis-induced fusion of LDL particles

Altered phospholipid-apoB-100 interactions and generation of extra membrane material in proteolysis-induced fusion of LDL particles

Lipid droplets and membrane material are produced in the extracellular matrix of the arterial intima during atherogenesis. Both in vitro and in vivo experimentation suggests that fusion of modified LDL particles leads to formation of such lipid droplets. Here we applied proton NMR spectroscopy to pr...

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Bibliographic Details
Main Authors: Markku O. Pentikäinen, Marja T. Hyvönen, Katariina Öörni, Tiia Hevonoja, Ari Korhonen, Erno M.P. Lehtonen-Smeds, Mika Ala-Korpela, Petri T. Kovanen
Format: Article
Language:English
Published: Elsevier 2001-06-01
Series:Journal of Lipid Research
Subjects:
arterial lipid accumulation
NMR spectroscopy
proteolytic LDL fusion
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520316151

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http://www.sciencedirect.com/science/article/pii/S0022227520316151

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