First application of chiral phosphotriesters in asymmetric metal catalysis: enantioselective Zn-catalyzed hydrosilylation of ketones in the presence of BINOL-derived phosphates
Chiral phosphotriesters are an unexplored class of ligands in metal catalysis. We wish to disclose herein the foremost application of novel chiral BINOL-derived mono- and bisphosphates in asymmetric zinc-catalyzed hydrosilylation of ketones. Corresponding alcohols were obtained in up to 92% yield an...
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| Format: | Article |
| Language: | English |
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Académie des sciences
2021-03-01
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| Series: | Comptes Rendus. Chimie |
| Subjects: | |
| Online Access: | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.67/ |
| _version_ | 1797651390439358464 |
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| author | Ngo Ndimba, Alphonsine Roisnel, Thierry Argouarch, Gilles Lalli, Claudia |
| author_facet | Ngo Ndimba, Alphonsine Roisnel, Thierry Argouarch, Gilles Lalli, Claudia |
| author_sort | Ngo Ndimba, Alphonsine |
| collection | DOAJ |
| description | Chiral phosphotriesters are an unexplored class of ligands in metal catalysis. We wish to disclose herein the foremost application of novel chiral BINOL-derived mono- and bisphosphates in asymmetric zinc-catalyzed hydrosilylation of ketones. Corresponding alcohols were obtained in up to 92% yield and 34% ee. |
| first_indexed | 2024-03-11T16:14:17Z |
| format | Article |
| id | doaj.art-7f047cb2c1744f8ab6eeef102052ecf5 |
| institution | Directory Open Access Journal |
| issn | 1878-1543 |
| language | English |
| last_indexed | 2024-03-11T16:14:17Z |
| publishDate | 2021-03-01 |
| publisher | Académie des sciences |
| record_format | Article |
| series | Comptes Rendus. Chimie |
| spelling | doaj.art-7f047cb2c1744f8ab6eeef102052ecf52023-10-24T14:22:52ZengAcadémie des sciencesComptes Rendus. Chimie1878-15432021-03-01241778110.5802/crchim.6710.5802/crchim.67First application of chiral phosphotriesters in asymmetric metal catalysis: enantioselective Zn-catalyzed hydrosilylation of ketones in the presence of BINOL-derived phosphatesNgo Ndimba, Alphonsine0Roisnel, Thierry1Argouarch, Gilles2Lalli, Claudia3Univ Rennes, CNRS, ISCR UMR 6226, F-35000 Rennes, FranceUniv Rennes, CNRS, ISCR UMR 6226, F-35000 Rennes, FranceUniv Rennes, CNRS, ISCR UMR 6226, F-35000 Rennes, FranceUniv Rennes, CNRS, ISCR UMR 6226, F-35000 Rennes, FranceChiral phosphotriesters are an unexplored class of ligands in metal catalysis. We wish to disclose herein the foremost application of novel chiral BINOL-derived mono- and bisphosphates in asymmetric zinc-catalyzed hydrosilylation of ketones. Corresponding alcohols were obtained in up to 92% yield and 34% ee.https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.67/Chiral phosphotriestersBINOLAsymmetric catalysisEnantioselective hydrosilylationKetones |
| spellingShingle | Ngo Ndimba, Alphonsine Roisnel, Thierry Argouarch, Gilles Lalli, Claudia First application of chiral phosphotriesters in asymmetric metal catalysis: enantioselective Zn-catalyzed hydrosilylation of ketones in the presence of BINOL-derived phosphates Comptes Rendus. Chimie Chiral phosphotriesters BINOL Asymmetric catalysis Enantioselective hydrosilylation Ketones |
| title | First application of chiral phosphotriesters in asymmetric metal catalysis: enantioselective Zn-catalyzed hydrosilylation of ketones in the presence of BINOL-derived phosphates |
| title_full | First application of chiral phosphotriesters in asymmetric metal catalysis: enantioselective Zn-catalyzed hydrosilylation of ketones in the presence of BINOL-derived phosphates |
| title_fullStr | First application of chiral phosphotriesters in asymmetric metal catalysis: enantioselective Zn-catalyzed hydrosilylation of ketones in the presence of BINOL-derived phosphates |
| title_full_unstemmed | First application of chiral phosphotriesters in asymmetric metal catalysis: enantioselective Zn-catalyzed hydrosilylation of ketones in the presence of BINOL-derived phosphates |
| title_short | First application of chiral phosphotriesters in asymmetric metal catalysis: enantioselective Zn-catalyzed hydrosilylation of ketones in the presence of BINOL-derived phosphates |
| title_sort | first application of chiral phosphotriesters in asymmetric metal catalysis enantioselective zn catalyzed hydrosilylation of ketones in the presence of binol derived phosphates |
| topic | Chiral phosphotriesters BINOL Asymmetric catalysis Enantioselective hydrosilylation Ketones |
| url | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.67/ |
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