Pre-Clinical Intravenous Serum Pharmacokinetics of Albumin Binding and Non-Half-Life Extended Nanobodies®

Nanobodies are antigen-binding, single variable domain proteins derived from naturally-occurring, heavy chain only antibodies. They are highly soluble, stable, and can be linked to build multi-specific formats. Several Nanobodies are currently in clinical development in different therapeutic areas,...

Full description

Bibliographic Details
Main Authors: Sven Hoefman, Ingrid Ottevaere, Judith Baumeister, Maria Laura Sargentini-Maier
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Antibodies
Subjects:
Online Access:http://www.mdpi.com/2073-4468/4/3/141