BNIP3 enhances pancreatic cancer cell migration and proliferation via modulating autophagy under hypoxia

BNIP3 enhances pancreatic cancer cell migration and proliferation via modulating autophagy under hypoxia

Chemotherapy and immunotherapy for pancreatic ductal adenocarcinoma (PDAC) have limited success for the intricated surrounding cancer microenvironment. Hypoxic microenvironment in PDAC causes the activation of multiple different molecules and signaling pathways compared with normoxia. We studied the...

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Bibliographic Details
Main Authors: Hongmei Li, Can Zhang, Qiong Zhang, Jiezhi Jia, Xiaojiao Wang
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Heliyon
Subjects:
BNIP3
Autophagy
ERK1/2
Pancreatic ductal adenocarcinoma
Hypoxia
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022024781

Internet

http://www.sciencedirect.com/science/article/pii/S2405844022024781

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