TNF receptors regulate vascular homeostasis in zebrafish through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3
SUMMARY Although it is known that tumor necrosis factor receptor (TNFR) signaling plays a crucial role in vascular integrity and homeostasis, the contribution of each receptor to these processes and the signaling pathway involved are still largely unknown. Here, we show that targeted gene knockdown...
Main Authors: | , , , , , , , , , |
---|---|
פורמט: | Article |
שפה: | English |
יצא לאור: |
The Company of Biologists
2013-03-01
|
סדרה: | Disease Models & Mechanisms |
גישה מקוונת: | http://dmm.biologists.org/content/6/2/383 |