Exploration of novel biomarkers in Alzheimer’s disease based on four diagnostic models

Exploration of novel biomarkers in Alzheimer’s disease based on four diagnostic models

BackgroundDespite tremendous progress in diagnosis and prediction of Alzheimer’s disease (AD), the absence of treatments implies the need for further research. In this study, we screened AD biomarkers by comparing expression profiles of AD and control tissue samples and used various models to identi...

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Bibliographic Details
Main Authors: Cuihua Zou, Li Su, Mika Pan, Liechun Chen, Hepeng Li, Chun Zou, Jieqiong Xie, Xiaohua Huang, Mengru Lu, Donghua Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
random forest model
least absolute shrinkage and selection operator
logistic regression model
gradient boosting machine
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1079433/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2023.1079433/full

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