Cationic Perylene Antivirals with Aqueous Solubility for Studies In Vivo

Cationic Perylene Antivirals with Aqueous Solubility for Studies In Vivo

Perylene-based compounds are attracting significant attention due to their high broad-spectrum antiviral activity against enveloped viruses. Despite unambiguous results of in vitro studies and high selectivity index, the poor water solubility of these compounds prevented in vivo evaluation of their...

Full description

Bibliographic Details
Main Authors: Anna A. Shtro, Anzhelika V. Garshinina, Vera A. Alferova, Polina N. Kamzeeva, Viktor P. Volok, Ekaterina S. Kolpakova, Timofei D. Nikitin, Alexey A. Chistov, Evgeny S. Belyaev, Vladimir A. Korshun, Liubov I. Kozlovskaya, Andrey V. Aralov
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceuticals
Subjects:
perylene
broad-spectrum antivirals
in vivo protective activity
solubility
influenza
Online Access:https://www.mdpi.com/1424-8247/15/10/1178

Internet

https://www.mdpi.com/1424-8247/15/10/1178

Similar Items