Neuroprotective Effect of Antiapoptotic URG7 Protein on Human Neuroblastoma Cell Line SH-SY5Y

Neuroprotective Effect of Antiapoptotic URG7 Protein on Human Neuroblastoma Cell Line SH-SY5Y

Up-regulated Gene clone 7 (URG7) is a protein localized in the endoplasmic reticulum (ER) and overexpressed in liver cells upon hepatitis B virus (HBV) infection. Its activity has been related to the attenuation of ER stress resulting from HBV infection, promoting protein folding and ubiquitination...

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Bibliographic Details
Main Authors: Ilaria Nigro, Rocchina Miglionico, Monica Carmosino, Andrea Gerbino, Anna Masato, Michele Sandre, Luigi Bubacco, Angelo Antonini, Roberta Rinaldi, Faustino Bisaccia, Maria Francesca Armentano
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
endoplasmic reticulum (ER) stress
unfolded protein response (UPR)
protein misfolding
PI3K/AKT pathway
autophagy
tunicamycin
Online Access:https://www.mdpi.com/1422-0067/25/1/481

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https://www.mdpi.com/1422-0067/25/1/481

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