Preparation and characterization of the myricetin-loaded solid lipid nanoparticles decorated with folic acid-bound chitosan and evaluation of its antitumor and anti-angiogenic activities in vitro and in vivo in mice bearing tumor models

Abstract Myricetin is a flavonoid with anticancer properties. This study aimed to formulate myricetin in the form of solid lipid nanoparticles (SLN), decorated with chitosan (CS) and active-targeted with folic acid (FA). After characterization, the in vitro release, cytotoxicity, antioxidant, and ab...

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Bibliographic Details
Main Authors: Niloufar Khatamian, Alireza Motavalizadehkakhky, Masoud Homayouni Tabrizi, Jamshid Mehrzad, Rahele Zhiani
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Cancer Nanotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12645-023-00160-3