Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy

Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy

Although being rare in absolute numbers, neuroblastoma (NB) represents the most frequent solid tumor in infants and young children. Therapy options and prognosis are comparably good for NB patients except for the high risk stage 4 class. Particularly in adolescent patients with certain genetic alter...

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Bibliographic Details
Main Authors: Anke Koeniger, Anna Brichkina, Iris Nee, Lukas Dempwolff, Anna Hupfer, Ilya Galperin, Florian Finkernagel, Andrea Nist, Thorsten Stiewe, Till Adhikary, Wibke Diederich, Matthias Lauth
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
neuroblastoma
hedgehog
GLI1
GLI3
primary cilia
ISX
Online Access:https://www.mdpi.com/2072-6694/13/8/1908

Internet

https://www.mdpi.com/2072-6694/13/8/1908

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