The HSP90 Inhibitor, AUY-922, Protects and Repairs Human Lung Microvascular Endothelial Cells from Hydrochloric Acid-Induced Endothelial Barrier Dysfunction

Exposure to hydrochloric acid (HCl) leads acutely to asthma-like symptoms, acute respiratory distress syndrome (ARDS), including compromised alveolo-capillary barrier, and respiratory failure. To better understand the direct effects of HCl on pulmonary endothelial function, we studied the characteri...

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Bibliographic Details
Main Authors: Ruben M. L. Colunga Biancatelli, Pavel Solopov, Betsy Gregory, John D. Catravas
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/6/1489