Impact of Lipid Composition and Receptor Conformation on the Spatio-temporal Organization of μ-Opioid Receptors in a Multi-component Plasma Membrane Model.

The lipid composition of cell membranes has increasingly been recognized as playing an important role in the function of various membrane proteins, including G Protein-Coupled Receptors (GPCRs). For instance, experimental and computational evidence has pointed to lipids influencing receptor oligomer...

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Bibliographic Details
Main Authors: Kristen A Marino, Diego Prada-Gracia, Davide Provasi, Marta Filizola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1005240