New models of large-cell neuroendocrine carcinoma and small-cell lung carcinoma
High-grade neuroendocrine lung carcinomas (LCNEC, SCLC) are recalcitrant cancers for which no optimal management has been achieved. We have recently described two models of LCNEC and SCLC developed upon inactivation of 4 tumor suppressors genes (Rb1 (RB transcriptional corepressor 1), Rbl1 (RB trans...
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Format: | Article |
Language: | English |
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Taylor & Francis Group
2020-03-01
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Series: | Molecular & Cellular Oncology |
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Online Access: | http://dx.doi.org/10.1080/23723556.2019.1702413 |