New models of large-cell neuroendocrine carcinoma and small-cell lung carcinoma

High-grade neuroendocrine lung carcinomas (LCNEC, SCLC) are recalcitrant cancers for which no optimal management has been achieved. We have recently described two models of LCNEC and SCLC developed upon inactivation of 4 tumor suppressors genes (Rb1 (RB transcriptional corepressor 1), Rbl1 (RB trans...

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Bibliographic Details
Main Author: Mirentxu Santos
Format: Article
Language:English
Published: Taylor & Francis Group 2020-03-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2019.1702413