Deconvolution of the MBP-Bri2 Interaction by a Yeast Two Hybrid System and Synergy of the AlphaFold2 and High Ambiguity Driven Protein-Protein Docking

Myelin basic protein (MBP) is one of the key proteins in the development of multiple sclerosis (MS). However, very few intracellular MBP partners have been identified up to now. In order to find proteins interacting with MBP in the brain, an expression library from the human brain was screened using...

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Bibliographic Details
Main Authors: Evgeniya V. Smirnova, Tatiana V. Rakitina, George A. Saratov, Anna A. Kudriaeva, Alexey A. Belogurov
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/12/2/197