IgAT (Immunoglobulin Analysis Tool): A novel tool for the analysis of human and mouse heavy and light chain transcripts

IgAT (Immunoglobulin Analysis Tool): A novel tool for the analysis of human and mouse heavy and light chain transcripts

Sequence analysis of immunoglobulin (Ig) heavy and light chain transcripts can refine categorization of B cell subpopulations and can shed light on the selective forces that act during immune responses or immune dysregulation, such as autoimmunity, allergy, and B cell malignancy. High-throughput seq...

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Bibliographic Details
Main Authors: Tobias eRogosch, Sebastian eKerzel, Kam Hon Hoi, Zhixin (Jason) eZhang, Rolf F. Maier, Gregory C. Ippolito, Michael eZemlin
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Immunology
Subjects:
rearrangement
Antibody repertoire
Deep sequencing
high-throughput analysis
Immunoglobulin heavy chain gene
immunoglobulin light chain gene
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00176/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00176/full

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