Long-term cultures of human pancreatic islets in self-assembling peptides hydrogels

Long-term cultures of human pancreatic islets in self-assembling peptides hydrogels

Human pancreatic islets transplantation is an experimental therapeutic treatment for Type I Diabetes. Limited islets lifespan in culture remains the main drawback, due to the absence of native extracellular matrix as mechanical support after their enzymatic and mechanical isolation procedure. Extend...

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Bibliographic Details
Main Authors: Amanda Marchini, Maria Gessica Ciulla, Barbara Antonioli, Alessandro Agnoli, Umberto Bovio, Virginia Visnoviz, Federico Bertuzzi, Fabrizio Gelain
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
human pancreatic islets
self-assembling peptides
biomimetic nanomaterial
three-dimensional cell cultures
type 1 diabetes mellitus
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1105157/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1105157/full

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