Evolving antibody evasion and receptor affinity of the Omicron BA.2.75 sublineage of SARS-CoV-2

Evolving antibody evasion and receptor affinity of the Omicron BA.2.75 sublineage of SARS-CoV-2

Summary: SARS-CoV-2 Omicron BA.2.75 has diversified into multiple subvariants with additional spike mutations and several are expanding in prevalence, particularly CH.1.1 and BN.1. Here, we investigated the viral receptor affinities and neutralization evasion properties of major BA.2.75 subvariants...

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Bibliographic Details
Main Authors: Qian Wang, Zhiteng Li, Yicheng Guo, Ian A. Mellis, Sho Iketani, Michael Liu, Jian Yu, Riccardo Valdez, Adam S. Lauring, Zizhang Sheng, Aubree Gordon, Lihong Liu, David D. Ho
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:iScience
Subjects:
SARS-CoV-2
BA.2.75 subvariants
evolutionary trajectories
convergent evolution
neutralizing monoclonal antibody
mRNA vaccine
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223023313

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http://www.sciencedirect.com/science/article/pii/S2589004223023313

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