Prognostic and predictive role of YKL-40 in anal squamous cell carcinoma: a serological and tissue-based analysis in a multicentric cohort

Prognostic and predictive role of YKL-40 in anal squamous cell carcinoma: a serological and tissue-based analysis in a multicentric cohort

IntroductionAnal squamous cell carcinoma (ASC) is a rare gastrointestinal malignancy showing an increased incidence over the past decades. YKL-40 is an immune modulator and pro-angiogenetic factor that showed a promising prognostic and predictive potential in several malignancies, but limited data a...

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Bibliographic Details
Main Authors: Alessandro Gambella, Rebecca Senetta, Enrico Costantino Falco, Alessia Andrea Ricci, Luca Mangherini, Cristian Tampieri, Jessica Fissore, Giulia Orlando, Tilde Manetta, Giulio Mengozzi, Massimiliano Mistrangelo, Luca Bertero, Paola Cassoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Medicine
Subjects:
radiochemotherapy
nigro protocol
immunohistochemistry
serum biomarkers
overall survival
response to treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1372195/full

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https://www.frontiersin.org/articles/10.3389/fmed.2024.1372195/full

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