Validated stability-indicating HPLC-DAD method for determination of the phosphodiesterase (PDE-4) inhibitor roflumilast
A comprehensive stability indicating HPLC with diode array detection method was developed for determination of the recently approved phosphodiesterase type 4 (PDE-4) inhibitor roflumilast (RFL). Effective chromatographic separation was achieved using Durashell C18 column (4.6 × 250 mm, 5 μm particle...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Faculty of Pharmacy, Cairo University
2014-06-01
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Series: | Bulletin of Faculty of Pharmacy Cairo University |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1110093114000143 |