Cytotoxic effect of combining two antisense oligonucleotides against telomerase rna component (hTR and mRNA of centromere protein B (CENP-B) in hepatocellular carcinoma cells

Cytotoxic effect of combining two antisense oligonucleotides against telomerase rna component (hTR and mRNA of centromere protein B (CENP-B) in hepatocellular carcinoma cells

Abstract Telomerase is a ribonucleoprotein enzyme that plays a crucial role in maintaining the malignancy and is responsible for cellular immortality and tumorigenesis. On another hand, Centromere protein B (CENP-B) plays an important role in cell cycle regulation and helping in the high rate prolif...

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Bibliographic Details
Main Authors: AHMED M. EL-DESOKY, YASSER B.M. ALI, ROBA M. TALAAT
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2022-07-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
Telomerase
hTR
CENP-B
antisense oligonucleotide
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000300808&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000300808&tlng=en

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