A novel thin plate spline methodology to model tissue surfaces and quantify tumor cell invasion in organ-on-chip models

A novel thin plate spline methodology to model tissue surfaces and quantify tumor cell invasion in organ-on-chip models

Organ-on-chip (OOC) models can be useful tools for cancer drug discovery. Advances in OOC technology have led to the development of more complex assays, yet analysis of these systems does not always account for these advancements, resulting in technical challenges. A challenging task in the analysis...

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Bibliographic Details
Main Authors: Elizabeth Elton, Carly Strelez, Nolan Ung, Rachel Perez, Kimya Ghaffarian, Danielle Hixon, Naim Matasci, Shannon M. Mumenthaler
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:SLAS Discovery
Subjects:
Organs-on-chips
Invasion
Imaging
Topographical methodology
Automated analysis
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S247255522400025X

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http://www.sciencedirect.com/science/article/pii/S247255522400025X

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