Nanostructured lipid carriers as a novel tool to deliver sclareol: physicochemical characterisation and evaluation in human cancer cell lines

Nanostructured lipid carriers as a novel tool to deliver sclareol: physicochemical characterisation and evaluation in human cancer cell lines

Sclareol (SC) is arousing great interest due to its cytostatic and cytotoxic activities in several cancer cell lines. However, its hydrophobicity is a limiting factor for its in vivo administration. One way to solve this problem is through nanoencapsulation. Therefore, solid lipid nanoparticles (SLN...

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Bibliographic Details
Main Authors: Gabriel Silva Marques Borges, Pedro Henrique Dias Moura Prazeres, Ângelo Malachias de Souza, Maria Irene Yoshida, José Mario Carneiro Vilela, Aline Teixeira Maciel e Silva, Mariana Silva Oliveira, Dawidson Assis Gomes, Margareth Spangler Andrade, Elaine Maria de Souza-Fagundes, Lucas Antônio Miranda Ferreira
Format: Article
Language:English
Published: Universidade de São Paulo 2021-10-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Cancer
Sclareol
Solid lipid nanoparticles
Nanostructured lipid carriers
Small-angle X-ray scattering
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502021000100511&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502021000100511&tlng=en

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