Bispidine Platform as a Tool for Studying Amide Configuration Stability

Bispidine Platform as a Tool for Studying Amide Configuration Stability

In this work, the solution conformations of seventeen 3,7-diacyl bispidines were studied by means of NMR spectroscopy including VT NMR experiments. The acyl groups included alkyl, alkenyl, aryl, hetaryl, and ferrocene moieties. The presence of syn/anti-isomers and their ratios were estimated, and so...

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Bibliographic Details
Main Authors: Dmitry P. Krut’ko, Alexey V. Medved’ko, Konstantin A. Lyssenko, Andrei V. Churakov, Alexander I. Dalinger, Mikhail A. Kalinin, Alexey O. Gudovannyy, Konstantin Y. Ponomarev, Eugeny V. Suslov, Sergey Z. Vatsadze
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
3,7-diazabicyclo[3.3.1]nonanes
dynamic stereochemistry
barriers of amide rotation
NMR spectroscopy
X-ray diffraction study
quantum chemical calculations
Online Access:https://www.mdpi.com/1420-3049/27/2/430

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https://www.mdpi.com/1420-3049/27/2/430

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