Disease modifying and antiangiogenic activity of 2-Methoxyestradiol in a murine model of rheumatoid arthritis

<p>Abstract</p> <p>Background</p> <p>A critical component of disease progression in rheumatoid arthritis (RA) involves neovascularization associated with pannus formation. 2-methoxyestradiol (2ME2) is a naturally occurring molecule with no known physiologic function, al...

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Bibliographic Details
Main Authors: Moore Elizabeth G, Strawn Steve J, Park Eun J, Plum Stacy M, Sidor Carolyn F, Fogler William E
Format: Article
Language:English
Published: BMC 2009-05-01
Series:BMC Musculoskeletal Disorders
Online Access:http://www.biomedcentral.com/1471-2474/10/46