Inhibition of Hsp110-STAT3 interaction in endothelial cells alleviates vascular remodeling in hypoxic pulmonary arterial Hypertension model

Inhibition of Hsp110-STAT3 interaction in endothelial cells alleviates vascular remodeling in hypoxic pulmonary arterial Hypertension model

Abstract Background Pulmonary arterial hypertension (PAH) is a progressive and devastating disease characterized by pulmonary vascular remodeling which is associated with the malignant phenotypes of pulmonary vascular cells. Recently, the effects of heat shock protein 110 (Hsp110) in human arterial...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Congke Zhao, Xiangyang Le, Mengqi Li, Yuanbo Hu, Xiaohui Li, Zhuo Chen, Gaoyun Hu, Liqing Hu, Qianbin Li
स्वरूप: लेख
भाषा:English
प्रकाशित: BMC 2023-11-01
श्रृंखला:Respiratory Research
विषय:
Pulmonary arterial Hypertension
Vascular remodeling
Heat shock protein 110
Protein-protein interaction
Pulmonary arterial endothelial cell
ऑनलाइन पहुंच:https://doi.org/10.1186/s12931-023-02600-5

इंटरनेट

https://doi.org/10.1186/s12931-023-02600-5

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