Cucurbitacins as potential anticancer agents: new insights on molecular mechanisms

Cucurbitacins as potential anticancer agents: new insights on molecular mechanisms

Abstract Since ancient times, plants have been an extensive reservoir of bioactive compounds with therapeutic interest for new drug development and clinical application. Cucurbitacins are a compelling example of these drug leads, primarily present in the plant kingdom, especially in the Cucurbitacea...

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Bibliographic Details
Main Authors: Carla Varela, Catarina Melim, Beatriz G. Neves, Javad Sharifi-Rad, Daniela Calina, Assem Mamurova, Célia Cabral
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Translational Medicine
Subjects:
Cucurbitacins
Chemical synthesis
Malignant tumor
Chemoprevention
Anticancer mechanisms
Molecular targets
Online Access:https://doi.org/10.1186/s12967-022-03828-3

Internet

https://doi.org/10.1186/s12967-022-03828-3

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