Estimating the Population Benefits of Blood Pressure Lowering: A Wide‐Angled Mendelian Randomization Study in UK Biobank

Estimating the Population Benefits of Blood Pressure Lowering: A Wide‐Angled Mendelian Randomization Study in UK Biobank

Background The causal relevance of elevated blood pressure for several cardiovascular diseases (CVDs) is uncertain, as is the population impact of blood pressure lowering. This study systematically assesses evidence of causality for various CVDs in a 2‐sample Mendelian randomization framework, and e...

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Bibliographic Details
Main Authors: Hannah Higgins, Amy M. Mason, Susanna C. Larsson, Dipender Gill, Claudia Langenberg, Stephen Burgess
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiovascular disease
genetic epidemiology
high blood pressure
hypertension
Mendelian randomization
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.021098

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.121.021098

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