Microsatellite Instable Colorectal Adenocarcinoma Diagnostics: The Advent of Liquid Biopsy Approaches

Microsatellite Instable Colorectal Adenocarcinoma Diagnostics: The Advent of Liquid Biopsy Approaches

The introduction of immunotherapy has revolutionized the oncological targeted therapy paradigm. Microsatellite instability (MSI) identifies a subgroup of colorectal cancers (CRCs) which respond to treatment with immune checkpoint inhibitors. Tissue biopsy is currently the gold standard for the asses...

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Bibliographic Details
Main Authors: Carlotta Ceccon, Valentina Angerilli, Cosimo Rasola, Letizia Procaccio, Marianna Sabbadin, Francesca Bergamo, Umberto Malapelle, Sara Lonardi, Matteo Fassan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
liquid biopsy
colorectal cancer
microsatellite Instability
immunotherapy
circulating tumor DNA
cancer screening
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.930108/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.930108/full

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