A proof-of-concept assay for quantitative and optical assessment of drug-induced toxicity in renal organoids

Abstract Kidneys are complex organs, and reproducing their function and physiology in a laboratory setting remains difficult. During drug development, potential compounds may exhibit unexpected nephrotoxic effects, which imposes a significant financial burden on pharmaceutical companies. As a result...

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Bibliographic Details
Main Authors: Jasmin Dilz, Isabel Auge, Kathrin Groeneveld, Stefanie Reuter, Ralf Mrowka
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-33110-5