A proof-of-concept assay for quantitative and optical assessment of drug-induced toxicity in renal organoids
Abstract Kidneys are complex organs, and reproducing their function and physiology in a laboratory setting remains difficult. During drug development, potential compounds may exhibit unexpected nephrotoxic effects, which imposes a significant financial burden on pharmaceutical companies. As a result...
Main Authors: | Jasmin Dilz, Isabel Auge, Kathrin Groeneveld, Stefanie Reuter, Ralf Mrowka |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-33110-5 |
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